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A 10-year-old child with cleft palate and delayed milestones is being treated for epilepsy. Which medication should be avoided due to the risk of causing neural tube defects?
Which of the following is a potential cause of microcephaly, challenging behavior, poor memory, and low birth weight?
A newborn baby is jittery and shaking. What is the likely cause of these symptoms?
What is a potential cause of a jittery child with overarousal two hours after delivery, an increased need for handling, and normal neonatal reflexes?
What is the most appropriate initial study design to investigate the side effects of a newly prescribed drug?
Which study design would be appropriate to investigate the association between depression and lithium level?
What study design was utilised in research assessing the effectiveness of trainee GPs in managing medical conditions in patients with schizophrenia?
What study design is appropriate for finding an appropriate cut-point for the Hamilton Depression Rating Scale to screen for depression using DSM-5 diagnostic criteria as the reference standard?
How can the effectiveness of teaching GP’s motivational interviewing in improving abstinence among patients with alcohol addiction in primary care be tested?
What study design is appropriate to determine whether there is an association between gross domestic product of various countries and the prevalence of schizophrenia?
What study design is appropriate to find out whether CBT is helpful in treating people with arachnophobia when only 8 patients with this phobia can be identified?
What is the mode of transmission of Down syndrome when it is transmitted equally by both parents?
Two radiologists independently review MRI results and their interpretations are compared. What is being assessed?
A new test for suicide is developed and it is observed that those who score higher on the test are more likely to commit suicide. What type of validity is being assessed?
The Galbraith plot is a graphical method that is primarily used for which of the following?
Which plot(s) can be used to check heterogeneity?
Which legal case involved a patient who was detained at a hospital without his consent, leading to discussions of the definition of deprivation of liberty in healthcare?
Which of the following drugs should you avoid with Tamoxifen?
Block randomization is primarily used for which of the following purposes in clinical trials?
Which drug would you choose for a 40+ year old woman who has completed detox for alcohol, is on Tramadol for chronic back pain, and has a history of ischemic heart disease and kidney problems. She would like a drug to maintain abstinence?
Which drug has effects on GABA and acts as an NMDA antagonist with multiple uses?
What would you give to a homeless man found with confusion, unstable gait, and double vision?
A 38-year-old female patient presents with chronic back pain and reports feeling increasingly helpless after her partner recently left her. Which of the following conditions is she MOST likely to be suffering from?
A patient presents with episodic low mood, palpitations, motor tension, and muscle aches. Which of the following conditions is most likely?
A patient presents with generalized pain across his body following a viral infection. Which of the following conditions is most likely?
A young man who has experimented with drugs presents with two episodes of seizures, sweating, rigidity, and tachycardia. Which of the following drugs is most likely responsible for his symptoms?
An unemployed lady presents to A&E with rigidity, tachycardia, hallucinations, and profuse sweating. Her friend thinks she may have been using an unknown recreational drug. Which drug has she likely taken?
Person with epilepsy brought to A&E with carbamazepine induced hyponatremia, also has depression. Which antidepressant would you choose?
Patient presented with memory issues for 8 months- GP suspected Alzheimer which of the following would make you consider an alternative diagnosis?
Which of the following cannot be a Comorbid diagnosis with recurrent depressive disorder?
Which of the following ECG findings is associated with tricyclic antidepressants?
Which of the following ECG findings is associated with donepezil?
A 24-year-old female with a known history of bulimia nervosa presents to the clinic for a routine check-up. An electrocardiogram (ECG) is performed as part of her evaluation. Which of the following ECG findings is most commonly associated with bulimia nervosa?
A 22-year-old female with a known history of an eating disorder presents to your clinic. Blood tests reveal mild hypokalemia. Which of the following electrocardiogram (ECG) findings is most commonly associated with mild hypokalemia in this patient?
What ECG finding is commonly seen in a person who has recently started on clozapine and reports chest pain?
What ECG finding is commonly seen in a person who has recently started on Citalopram and undergoes routine ECG?
What is the appropriate next step for an 80-year-old woman who was recently started on Donepezil and presented with ankle swelling?
What is the most appropriate antipsychotic for a 74-year-old man who needs to commence an antipsychotic but his eGFR is >25ml/min?
What could explain the presentation of a 14 year old female who reportedly took an overdose of Paracetamol after a fight with boyfriend, presented with flushed face, tongue, confusion, MMSE- 21/30, and psychotic features. Which of the following can explain the presentation?
Which of the following gait will you see in an upper motor neuron lesion?
Which outcome measure takes into account the quality of life of patients?
What is the best way to help a severely autistic child understand visits from their mother that may cause agitation?
What intervention may be appropriate for a patient who finds it funny when others imitate his behavior?
How would you best communicate to someone with a learning disabilities who struggles to understand a flow of events regarding about what activities are happening now and next?
What is the best predictor of violence?
What is the primary cause of violent acts such as homicide and theft?
In cases of amnesia following a violent offense, which of the following is true?
What is the approximate incidence of stroke in patients with schizophrenia taking antipsychotic medication?
What is the legal term for a woman who kills her baby due to psychosis and claims she was “ending the misery” of the sick child?
What is ICER?
What is cost benefit analysis used for in health economics?
What is the likely diagnosis for a patient with severe self-harm behavior and a history of hyperuricemia and gout?
Which database is a freely accessible search engine that primarily includes biomedical literature and is maintained by the US National Library of Medicine?
What type of graph is typically used to display the results of a meta-analysis?
What is priming in statistics?
What is an odds ratio?
What is the formula for odds ratio?
What does an ICER curve represent?
What is standard deviation?
What is a funnel plot used for in meta-analysis?
What is the reason for imputation in statistics?
What type of bias causes asymmetry in a funnel plot examining the results of a meta-analyses?
What is the likely effect of imputation on the pooled effect size reported in a meta-analysis?
What is a CONSORT diagram typically used for in clinical research studies?
Which of the following is NOT a type of family therapy?
Which of the following is a type of psychodynamic therapy?
What is the most likely diagnosis for a female who presents to A&E with sudden aphonia after her mother came to live with them?
What is the most likely diagnosis for a noncompliant patient on antipsychotics who is using amphetamines and presents with mutism, catalepsy, and fever, and is not currently on antipsychotics?
A patient with a parietal lobe infarct is agitated and confused. Which of the following would be appropriate to give?
A 33-year-old female with moderate intellectual disability and mania is being treated. Which of the following medications would you not prescribe?
A female in her 30s presents with a 3-day history of mutism and immobility. What would you do first?
What is the next step for an elderly female presented with QTc of 490ms and is on Sertraline 50mg and Risperidone 2mg?
What is the next step for a woman on Citalopram 40mg for 2 months, with no response to treatment?
Which non-parametric test is used to compare the median of two independent groups?
What statistical analysis is used to compare group means while controlling for a continuous variable?
What statistical analysis is used to compare the means of three or more groups?
What statistical analysis is used to compare the means of two groups?
What statistical analysis is used to compare the distribution of categorical variables between two or more groups?
What statistical analysis is used to model the relationship between a dependent variable and one or more independent variables?
An elderly patient wants to know how to reduce his risk of dementia. From the options he suggests what would be the best to recommend?
Which of the following is unethical for cannabis and psychosis research?
Prevalence of depression in European countries with different socioeconomic levels was investigated. Which study design was used?
What research method would you use to get views of multiple MDT members about the role of a psychiatrist in their team?
What is triangulation in medical statistics?
What is grounded theory in research?
What is reflexivity in statistics?
What do skewed results in a histogram indicate?
What is the Kaplan-Meier estimator used for?
What is the significant reason for lower life expectancy in schizophrenia?
Which of the following is a symptom of lithium toxicity?
Which of the following is a common extrapyramidal side effect (EPSE) seen in patients on antipsychotic medication?
What is the likely diagnosis of a mother who experienced a traumatic birth of her child, who is currently 18months post the child’s birth struggling with distressing and intrusive thoughts of her harming the baby. She finds these thoughts anxiety provoking. What is her likely diagnosis?
What is the most likely diagnosis for a 32-year-old woman who is 14 weeks post-partum and presents with poor sleep, inability to enjoy activities, fatigue, irritability, and a fear that the baby will catch germs from everything in the house?
What is the statistical method used to analyse the relationship between a dependent variable and one or more independent variables?
What is the second-line treatment for obsessive-compulsive disorder (OCD)?
What is number needed to treat (NNT)?
BDI is a questionnaire that assesses the severity of which of the following?
What is the most appropriate next step in the management of a 39-year-old man with schizoaffective disorder taking Risperidone 1mg twice daily and Citalopram 20mg daily who presents to the outpatient clinic with a tremor?
What is a key role for CBT in psychosis?
Availability of a therapist for telephone contact between appointments is one of the approaches used in which therapy?
What is systematic desensitization?
What is cognitive dissonance?
Which of the following is a principle of motivational interviewing?
What is a commonly used policy measure to reduce alcohol consumption?
What is the prevalence of antisocial personality disorder in the UK prison system?
Is remission of symptoms possible for individuals diagnosed with emotionally unstable personality disorder (EUPD)?
Which of the following disorders increases in severity and prevalence between 9-11 years old?
What is the estimated heritability percentage of Autism Spectrum Disorder (ASD)?
What is the highest risk factor for suicide in prison?
What is the leading cause of death among young people aged 15-29 worldwide?
Which genetic disorder is associated with an increased risk of psychosis?
Which genetic disorder has an equal prevalence in males and females?
What is the approximate prevalence rate of schizophrenia in children and adolescents?
What is a key difference between sleep terrors and nightmares?
Which symptom is commonly associated with narcolepsy?
What is a potential benefit of melatonin use in children with sleep problems?
What is a potential effect of using melatonin in children with sleep problems?
Which of the following conditions is commonly associated with theft?
What is the purpose of intention to treat (ITT) analysis in a clinical trial?
What is the purpose of sequential diagrammatic reformulation (SDR) in cognitive analytical therapy (CAT)?
In which of the following therapies diagrammatic reformulations are used to represent the reciprocal roles that are dominant in one’s relationships with others?
Which type of conditioning is thought to maintain compulsive behaviours in OCD?
Which of the following study designs is commonly used to investigate the association between an exposure and an outcome?
In which of the following conditions is clozapine contraindicated?
Which of the following is a finding from the CUtLASS study?
What was the main finding of the CUtLASS study?
What is a negative therapeutic reaction?
In schizophrenia, which cognitive function is most likely to be impaired?
Which cognitive domain is most commonly impaired in patients with schizophrenia?
What is the MATRICS Consensus Cognitive Battery?
What symptom of ADHD does Clonidine not improve?
A 12 year-old boy presents to outpatient clinic with motor tics and facial grimacing for 6 months. What is the most likely diagnosis?
What does the ROC curve measure in diagnostic accuracy?
In an allocation scheme, the following allocation of a subject depends on the characteristics of those already allocated. This scheme can be called?
To ensure comparability, the case and control groups in a study can be matched based on which technique?
What is a short-acting stimulant and full agonist used in the treatment of opioid addiction?
What is the recommended initial management for a 10-year-old child presenting with mild depression?
What is a recommended psychotherapy for a child with PTSD?
What is the estimated prevalence of Autism Spectrum Disorder (ASD) among the UK prison population?
What is an important consideration when conducting research involving participants with learning difficulties?
A lady who is 12 weeks pregnant reports she wants to stop her methadone script of 70mg/daily. What would you advise?
What is the percentage of individuals with Borderline Personality Disorder (BPD) who show improvement within a 10-year period?
What is the best predictor of successful response to electroconvulsive therapy (ECT)?
A 35 year-old man is a long-term user of cocaine. Which of his cognitive domains is most likely to have been affected as a result of this substance misuse?
What is the most common symptom seen in Alzheimer’s disease?
What is the most common behavioural symptom seen in Alzheimer’s disease?
What percentage of severe dementia cases suffer from a stroke within 12 weeks?
What is a full opioid agonist used in the treatment of opioid addiction?
Considering the correlation between hashish use and first-episode psychosis, which of the following specific conditions or factors is most likely to increase the susceptibility to first-episode psychosis in individuals who are heavy and frequent hashish users?
Which of the following study designs is best suited for investigating the effectiveness of a medical intervention in a group of individuals over a period of time?