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The elimination of ethanol primarily follows zero-order kinetics when the blood alcohol concentration (BAC) is at or above a moderate level. This is because the enzymes responsible for alcohol metabolism, mainly alcohol dehydrogenase (ADH) in the liver, become saturated. 

Location: 4.2 Pharmacokinetics Quiz

The elimination of ethanol primarily follows zero-order kinetics when the blood alcohol concentration (BAC) is at or above a moderate level. This is because the enzymes responsible for alcohol metabolism, mainly alcohol dehydrogenase (ADH) in the liver, become saturated. 

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