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The most commonly used direct gene analysis methods for detecting genetic mutations involve Polymerase Chain Reaction (PCR) to amplify specific DNA regions followed by Sanger sequencing to determine the precise DNA sequence and identify any changes. Other advanced and increasingly common methods include various forms of Next-Generation Sequencing (NGS), which offers higher throughput for larger-scale analysis and is being used in clinical settings. 

Location: 3.7 Genetics Quiz

The most commonly used direct gene analysis methods for detecting genetic mutations involve Polymerase Chain Reaction (PCR) to amplify specific DNA regions followed by Sanger sequencing to determine the precise DNA sequence and identify any changes. Other advanced and increasingly common methods include various forms of Next-Generation Sequencing (NGS), which offers higher throughput for larger-scale analysis and is being used in clinical settings. 

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